Pre-Conference Workshop Day
Tuesday, January 24 | 9:00am - 1:00pm
9.00 Registration & Coffee Networking Room Opens
WORKSHOP A - 10am - 1pm
Modifying RNA, Delivery & Cellular Products to Avoid Immunogenecity to Accelerate Safe RNA-Based Cellular Therapeutics Through to Clinical Development
- Deep-diving into modifications and packaging methods to decrease immunogenicity of RNA within cellular products to evade immune responses to prevent rejection and severe immune responses
- Preventing immunogenicity of receptors to RNA within a cell product
- Taking learnings from vaccines for infectious disease treatment to clarify the feasibility of non-immunogenic mRNA expansion in cellular products for oncology treatment
- Elucidating the clinical impacts of immunogenicity on persistence, ability to retreat and re-dose to clarify the clinical benefit
- Harnessing assays to predict innate sensing in a preclinical stage to advance to the clinic
Workshop Leaders:
Dharini Shah
Senior Research
Director,
Immunology
Tidal Therapeutics
– (a Sanofi
Company)
David Peritt
Founder & CSO
Lupagen
Gilles Besin
CSO
Orbital
Therapeutics
Cory Sago
Co-Founder & CEO
New Stealth
Company